Staff Research Associate

MED-ZSFG-AIDS

Full Time

77345BR

Job Summary

The UCSF Hair Analytical Laboratory (HAL) analyzes antiretroviral, anti-tuberculosis (anti-TB), antibiotic, and controlled substance concentrations in hair (but may include other biological specimens such as urine, dried blood spot (DBS), whole blood, plasma, serum, nail, saliva, etc.) in the context of HIV and TB prevention and treatment studies using assays that are developed and validated according to the Federal Drug Administration (FDA's) guidelines for bioanalytical methods and the National Institute of Health's (NIH's) Division of AIDS' (DAIDS) Clinical Pharmacology Quality Assurance Program (CPQA). This position is responsible for overseeing and maintaining high-quality regulatory functions in the laboratory.

This position will assist senior analysts and train and mentor junior analysts to determine drug concentrations in samples utilizing validated high-performance liquid chromatographic (HPLC)-tandem mass spectrometric (LC/MS/MS) bioanalytical methods.

The purpose of this position is to design, develop, and execute a variety of analytical methods to quantitate antiretroviral, anti-TB, antibiotic drugs, controlled substances, and/or other biomarkers using liquid chromatography-tandem mass spectrometry (LC-MS/MS), primarily in hair samples (but may include other biological specimens, such as urine, DBS, whole blood, plasma, serum, nail, saliva, etc.), for pharmacokinetic, compliance, and efficacy studies. Techniques may include, but not limited to, protein precipitation, liquid-liquid extraction (LLE), and solid phase extraction (SPE).

The successful candidate will have some knowledge and engage in analytical LC/MS/MS method development, validation, and the assaying of clinical samples in compliance with the Food and Drug Administration's (FDA's) Good Laboratory Practice (GLP) and National Institute of Health's (NIH's Division of AIDS' (DAIDS) Clinical Pharmacology Quality Assurance (CPQA) regulatory guidelines (DAIDS) Clinical Pharmacology Quality Assurance (CPQA) regulatory guidelines.

In addition, be required to prepare Standard Operating Procedures (SOPs) and Analytical Validation Reports (AVR) for submission to Clinical Pharmacology Quality Assurance (CPQA); respond to inquiries from CPQA; train and mentor new staff members after completing and understanding internal laboratory SOPs; operate and calibrate analytical instruments; use and calibrate micropipettes; prepare, analyze, run, and interpret data; and thoroughly document in lab books, log books, and paperwork.

The final salary and offer components are subject to additional approvals based on UC policy.

To see the salary range for this position (we recommend that you make a note of the job code and use that to look up): TCS Non-Academic Titles Search (https://tcs.ucop.edu/non-academic-titles)

Please note: An offer will take into consideration the experience of the final candidate AND the current salary level of individuals working at UCSF in a similar role.

For roles covered by a bargaining unit agreement, there will be specific rules about where a new hire would be placed on the range.

To learn more about the benefits of working at UCSF, including total compensation, please visit: https://ucnet.universityofcalifornia.edu/compensation-and-benefits/index.html

Department Description

The Division of HIV, Infectious Diseases and Global Medicine at UCSF is an internationally recognized global leader in clinical care, research and education. With its home-base located at ZSFG, the Division has been ranked as the top facility in the country for AIDS care for over ten years. The Division's work is featured frequently in the media, and it is often visited by international, national, state and local dignitaries and delegations. The Division consists of approximately 36 faculty members and 140 academic and staff employees. It is the largest Division of the Department of Medicine at ZSFG, with a total expenditure budget of approximately $45 million dollars.

Required Qualifications

• One year related scientific techniques and procedures as learned from academic laboratory or field experimental experience, especially utilizing LC-MS/MS systems (preferably Micromass Quattro Ultima (MassLynx software), Sciex API 5000 (Analyst software), and/or Agilent 6495 (MassHunter software) and HPLC systems
• BA/BS in a related science including one year of recent/directly related work experience following degree completion, utilizing the techniques/methods required by the position; or an equivalent combination of education and experience
• Demonstrate reliability, organizational skills, attention to detail, and record keeping abilities based on prior experience
• Outstanding communication skills
• Strong basic laboratory techniques, such as micropipetting; measuring solutions using volumetric flasks and graduated cylinders; making reagents, mobile phases, and standard solutions; using centrifuges, vortexers, and other equipment in an analytical laboratory
• Computer software skills (MS Word, Excel and PowerPoint)

Preferred Qualifications

• One year of Laboratory Data Management System (LDMS) experience
• Knowledge of the basic principles in chemistry
• Strong lab book preparation and documentation skills
• Prior knowledge in the US FDA Good Laboratory Practices (GLP) and the NIH DAIDS Clinical Pharmacology Quality Assurance (CPQA) regulations

About UCSF

The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and excellence in patient care. It is the only campus in the 10-campus UC system dedicated exclusively to the health sciences. We bring together the world's leading experts in nearly every area of health. We are home to five Nobel laureates who have advanced the understanding of cancer, neurodegenerative diseases, aging and stem cells.

Pride Values

UCSF is a diverse community made of people with many skills and talents. We seek candidates whose work experience or community service has prepared them to contribute to our commitment to professionalism, respect, integrity, diversity and excellence - also known as our PRIDE values.

In addition to our PRIDE values, UCSF is committed to equity - both in how we deliver care as well as our workforce. We are committed to building a broadly diverse community, nurturing a culture that is welcoming and supportive, and engaging diverse ideas for the provision of culturally competent education, discovery, and patient care. Additional information about UCSF is available at

Join us to find a rewarding career contributing to improving healthcare worldwide.

Equal Employment Opportunity

The University of California San Francisco is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, protected veteran or disabled status, or genetic information.

Organization

Campus

Job Code and Payroll Title

009617 SRA 2 NEX

Job Category

Research and Scientific

Bargaining Unit

University Professional Technical Employees - Research Support Professionals Unit (UPTE-RX)

Employee Class

Career

Percentage

100%

Location

Parnassus Heights (SF)

Shift

Days

Shift Length

8 Hours

Additional Shift Details

M - F 8 am to 5 pm